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Oral anticoagulants/LMW heparins provide comparable safety in antithrombotic prophylaxis
February 2017
Oral anticoagulants/LMW heparins provide comparable safety in antithrombotic prophylaxis
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A
Major Bleeding and Case Fatality Rate with the Direct Oral Anticoagulants in Orthopedic Surgery: A Systematic Review and Meta-Analysis
Semin Thromb Hemost. 2016 Feb;42(1):42-54Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
25 randomized controlled trials (RCTs) investigating the safety of direct oral anticoagulants and low molecular weight heparin/fondaparinux in antithrombotic prophylaxis during total hip replacement, total knee replacement, and hip fracture surgery were included. This meta-analysis was conducted in order to determine if direct oral anticoagulants, in addition to the more convenient oral administra...
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