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Combined IV and topical tranexamic acid reduces blood loss, not transfusion rate, in TKA
July 2016
Combined IV and topical tranexamic acid reduces blood loss, not transfusion rate, in TKA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Combined Administration of Systemic and Topical Tranexamic Acid for Total Knee Arthroplasty: Can It Be a Better Regimen and Yet Safe? A Randomized Controlled Trial
J Arthroplasty. 2016 Feb;31(2):542-7Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
119 patients scheduled for primary unilateral total knee arthroplasty were randomized to undergo the procedure either with combined intravenous and topical administration of tranexamic acid, or intravenous TXA administration alone. The purpose of this study was to compare total blood loss, allogeneic transfusion rate, hemoglobin drop, and the incidence of thromboembolic complications between group...
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