Addition of diluted epinephrine to topical TXA for reducing blood loss in THA
Topical Application of Tranexamic Acid Plus Diluted Epinephrine Reduces Postoperative Hidden Blood Loss in Total Hip ArthroplastyJ Arthroplasty. 2015 Dec;30(12):2196-200
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107 patients scheduled for total hip arthroplasty without the use of postoperative drains were randomized to be administered topical tranexamic acid (TXA) with or without the addition of diluted epinephrine (DEP). The purpose of this study was to evaluate if the addition of DEP to topical TXA significantly reduced haemtological parameters associated with blood loss and allogeneic blood transfusion...
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