Cyclobenzaprine or oxycodone show no benefit to naproxen treatment of acute low back pain
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical TrialJAMA. 2015 Oct 20;314(15):1572-80.
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323 patients with acute low back pain were randomized to receive naproxen with 1 of 3 concurrent medications: cyclobenzaprine, oxycodone/acetaminophen, or a placebo. The purpose of the study was to compare the efficacy of these treatments and determine if the addition of these skeletal muscle relaxants and opioids to naproxen treatment provided further benefits to the patient. Improvement to RMDQ ...
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