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Greater BMD after 1 year for ALN/D5600 compared to calcitriol treatment in osteoporosis

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Ace Report Cover
February 2016

Greater BMD after 1 year for ALN/D5600 compared to calcitriol treatment in osteoporosis

Vol: 5| Issue: 2| Number:26| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Alendronate sodium/vitamin D3 combination tablet versus calcitriol for osteoporosis in Chinese postmenopausal women: a 6-month, randomized, open-label, active-comparator-controlled study with a 6-month extension

Osteoporos Int. 2015 Sep;26(9):2365-74.

Contributing Authors:
ZL Zhang EY Liao WB Xia H Lin Q Cheng L Wang YQ Hao DC Chen H Tang Y De Peng L You L He ZH Hu CL Song F Wei J Wang L Zhang AC Santora

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Synopsis

219 postmenopausal Chinese women with osteoporosis were randomized to receive one of two medications: a weekly dose of alendronate sodium with vitamin D3 (ALN/D5600) or a daily dose of calcitriol. The purpose of the study was to determine if ALN/D5600 provided greater benefits for bone mineral density and other measures of osteoporosis compared to calcitriol and to assess the safety of alendronate...

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