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Liposomal bupivacaine vs. bupivacaine: same analgesic efficacy and narcotic use after TKA

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Ace Report Cover
December 2015

Liposomal bupivacaine vs. bupivacaine: same analgesic efficacy and narcotic use after TKA

Vol: 4| Issue: 12| Number:10| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Does Extended-Release Liposomal Bupivacaine Better Control Pain Than Bupivacaine After Total Knee Arthroplasty (TKA)? A Prospective, Randomized Clinical Trial

J Arthroplasty. 2015 Sep;30(9 Suppl):64-7

Contributing Authors:
WC Schroer PG Diesfeld AR LeMarr DJ Morton ME Reedy

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Synopsis

111 patients undergoing primary unilateral total knee arthroplasty were randomized to receive a periarticular injection of either liposomal bupivacaine or bupivacaine during surgery, as part of a multimodal analgesic protocol. The purpose of this study was to determine how liposomal bupivacaine compared to bupivacaine injection alone in terms of pain and narcotic use. The results indicated no diff...

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