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Comparison of two hyaluronan preperations to placebo for injection treatment of knee OA

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Ace Report Cover
January 2016

Comparison of two hyaluronan preperations to placebo for injection treatment of knee OA

Vol: 5| Issue: 1| Number:55| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Comparison of two hyaluronan drugs and placebo in patients with knee osteoarthritis. A controlled, randomized, double-blind, parallel-design multicentre study

Rheumatology (Oxford). 2002 Nov;41(11):1240-8.

Contributing Authors:
J Karlsson LS Sjögren LS Lohmander

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Synopsis

246 patients age 60 or older with knee osteoarthritis were randomized to 1 of 3 groups: one group received three intra-articular injections of Artzal hyaluronan, one group received three intra-articular injections of Synvisc hyaluronan, and one group received three intra-articular injections of placebo. The primary outcomes of interest were weight-bearing pain 26 weeks after treatment, and the per...

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