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Volume:5 Issue:1 Number:23 ISSN#:2563-5476
RCT
ACE Report #8172
Ace Report Cover Osteoarthritis

Hyaluronic acid injections reduce IL-1B and severity of knee OA after 5 weeks


How to Cite

OrthoEvidence. Hyaluronic acid injections reduce IL-1B and severity of knee OA after 5 weeks. ACE Report. 2016;5(1):23. Available from: https://myorthoevidence.com/AceReport/Report/8172

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

The effect of sodium hyaluronate treating knee osteoarthritis on synovial fluid interleukin -1β and clinical treatment mechanism

Pak J Pharm Sci. 2015 Jan;28(1 Suppl):407-10.

Contributing Authors: L Yang J Zhang G Wang

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Synopsis

40 patients with osteoarthritis of the knee were randomized to receive either intra-articular hyaluronic acid injections or placebo injections weekly, for 5 weeks. The purpose of the study was to compare the interleukin-1B content of the knee joint synovial fluid and the severity of knee osteoarthritis in these patients and with a healthy control group, before and after treatment. The results indi...

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