Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
Volume:5 Issue:1 Number:23 ISSN#:2563-5476
ACE Report #8172
Ace Report Cover Osteoarthritis

Hyaluronic acid injections reduce IL-1B and severity of knee OA after 5 weeks

How to Cite

OrthoEvidence. Hyaluronic acid injections reduce IL-1B and severity of knee OA after 5 weeks. ACE Report. 2016;5(1):23. Available from: https://myorthoevidence.com/AceReport/Report/8172

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

The effect of sodium hyaluronate treating knee osteoarthritis on synovial fluid interleukin -1β and clinical treatment mechanism

Pak J Pharm Sci. 2015 Jan;28(1 Suppl):407-10.

Contributing Authors: L Yang J Zhang G Wang

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here


40 patients with osteoarthritis of the knee were randomized to receive either intra-articular hyaluronic acid injections or placebo injections weekly, for 5 weeks. The purpose of the study was to compare the interleukin-1B content of the knee joint synovial fluid and the severity of knee osteoarthritis in these patients and with a healthy control group, before and after treatment. The results indi...

CME Image

Continuing Medical Education Credits

You could be earning 0.5 CME credits for each report you read.

For Reprints and Permissions, click here

Please Login or Join to leave comments.