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Volume:5 Issue:1 Number:20 ISSN#:2564-2537
Author Verified
RCT
ACE Report #8159
Ace Report Cover Osteoarthritis

Knee OA: greater reduction in pain after walking with high-molecular-weight HA vs saline


How to Cite

OrthoEvidence. Knee OA: greater reduction in pain after walking with high-molecular-weight HA vs saline. ACE Report. 2016;5(1):20. Available from: https://myorthoevidence.com/AceReport/Report/8159

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

A double-blind, randomized, saline-controlled study of the efficacy and safety of EUFLEXXA for treatment of painful osteoarthritis of the knee, with an open-label safety extension (the FLEXX trial)

.2009....

Contributing Authors: RD Altman JE Rosen DA Bloch HT Hatoum P Korner

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Synopsis

588 patients diagnosed with Kellgren-Lawrence grade II-II knee osteoarthritis were randomized to receive three weekly intra-articular injections of either hyaluronic acid (EUFLEXXA; Ferring Pharmaceuticals, Inc.) or saline placebo. The purpose of this study was to compare changes in pain, function and patient global assessment between the two groups. Follow-up was performed for 26 weeks following ...

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