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Knee OA: greater reduction in pain after walking with high-molecular-weight HA vs saline

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Ace Report Cover
January 2016

Knee OA: greater reduction in pain after walking with high-molecular-weight HA vs saline

Vol: 5| Issue: 1| Number:20| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

A double-blind, randomized, saline-controlled study of the efficacy and safety of EUFLEXXA for treatment of painful osteoarthritis of the knee, with an open-label safety extension (the FLEXX trial)

.2009....

Contributing Authors:
RD Altman JE Rosen DA Bloch HT Hatoum P Korner

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Synopsis

588 patients diagnosed with Kellgren-Lawrence grade II-II knee osteoarthritis were randomized to receive three weekly intra-articular injections of either hyaluronic acid (EUFLEXXA; Ferring Pharmaceuticals, Inc.) or saline placebo. The purpose of this study was to compare changes in pain, function and patient global assessment between the two groups. Follow-up was performed for 26 weeks following ...

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