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Hyaluronan injection beneficial for OA patients over age 65 with poor baseline function

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Ace Report Cover
January 2016

Hyaluronan injection beneficial for OA patients over age 65 with poor baseline function

Vol: 5| Issue: 1| Number:51| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Intra-articular hyaluronan injections in the treatment of osteoarthritis of the knee: a randomised, double blind, placebo controlled multicentre trial. Hyaluronan Multicentre Trial Group

Ann Rheum Dis. 1996 Jul;55(7):424-31.

Contributing Authors:
LS Lohmander N Dalén G Englund M Hämäläinen EM Jensen K Karlsson M Odensten L Ryd I Sernbo O Suomalainen A Tegnander

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Synopsis

240 patients aged 40-75 with knee osteoarthritis (OA) were randomized to receive 5 weekly injections of hyaluronan, or to receive 5 placebo injections. The purpose of the study was to determine the effects of hyaluronan injection on OA symptoms and knee function, up to 20 weeks after the start of treatment. Primary outcomes of interest were visual analogue scale (VAS) results for pain and disease ...

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