ACE Report #8037
Ace Report Cover Arthroplasty

Effect of local infiltration analgesia vs placebo on pain and opioid consumption in TKA

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:2

Local infiltration analgesia following total knee arthroplasty: effect on post-operative pain and opioid consumption-a meta-analysis

Knee Surg Sports Traumatol Arthrosc. 2015 Jul;23(7):1956-63.

Contributing Authors: R Keijsers R van Delft MP van den Bekerom DC de Vries RM Brohet PA Nolte

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7 randomized trials comparing the use of local infiltration analgesia (LIA) versus placebo in total knee arthroplasty were included in this meta-analysis. The purpose of this study was to evaluate pain scores and opioid consumption over the first 2 days postoperatively. Pooled analyses demonstrated significantly lower pain and opioid consumption among LIA-treated groups compared to placebo-treated...

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