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RCT
ACE Report #7825
Ace Report Cover Pediatric Orthopaedics

NSAIDs effect on blood pressure safe over 6 weeks in pediatric patients with JIA


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

The effects of celecoxib or naproxen on blood pressure in pediatric patients with juvenile idiopathic arthritis

Clin Med Insights Pediatr. 2015 May 4;9:55-62

Contributing Authors: B Falkner M Berger P Bhadra Brown D Iorga RW Nickeson L Zemel

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Synopsis

201 patients with juvenile idiopathic arthritis (JIA) were randomized to a naproxen group or a celecoxib group to compare the changes in systolic blood pressure (SBP) over 6 weeks, for the purpose of analyzing the safety and efficacy of NSAID treatment in pediatric patients. Results showed no significant changes in SBP in either group, with no difference between groups, and similar adverse events ...

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