ACE Report #7819
Ace Report Cover Arthroplasty

Perioperative gabapentin does not reduce postoperative morphine consumption after THA

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Randomized controlled trial of gabapentin as an adjunct to perioperative analgesia in total hip arthroplasty patients

Can J Anaesth. 2015 May;62(5):476-84

Contributing Authors: JE Paul M Nantha-Aree N Buckley U Shahzad J Cheng L Thabane A Tidy J DeBeer M Winemaker D Wismer D Punthakee V Avram

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102 patients undergoing primary total hip arthroplasty (THA) were randomized to receive either gabapentin or a placebo preoperatively and for two days postoperatively. The purpose of this study was to determine if gabapentin was effective in reducing postoperative morphine consumption and morphine-associated adverse events. Results demonstrated no significant differences between groups in total mo...

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