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Vol:4 Issue:11 Number:19 ISSN#:2564-2537
Author Verified
ACE Report #7817
Ace Report Cover General Orthopaedics

Bisphosphonates for fracture prevention in osteogenesis imperfecta patients

How to Cite

OrthoEvidence. Bisphosphonates for fracture prevention in osteogenesis imperfecta patients. ACE Report. 2015;4(11):19. Available from:

Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Bisphosphonates for the Prevention of Fractures in Osteogenesis Imperfecta: Meta-Analysis of Placebo-Controlled Trials

J Bone Miner Res. 2015 May;30(5):929-33

Contributing Authors: JD Hald E Evangelou BL Langdahl SH Ralston

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6 randomized controlled trials (RCTs) with a total of 424 subjects and 751 patient-years of follow-up were included in this meta-analysis. The purpose of this study was to determine the effectiveness of bisphosphonates in the prevention of fractures in patients with osteogenesis imperfecta. Pooled results demonstrated that bisphosphonates did not significantly reduce the proportion of patients wit...

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