TXA is effective and safe for reducing blood loss and transfusion in TKA patients
Is tranexamic acid clinically effective and safe to prevent blood loss in total knee arthroplasty? A meta-analysis of 34 randomized controlled trialsEur J Orthop Surg Traumatol. 2015 Apr;25(3):525-41
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34 randomized controlled trials (2,594 patients) were used in this meta-analysis analyzing the safety and efficacy of tranexamic acid (TXA) in patients undergoing primary total knee arthroplasty (TKA). Pooled results demonstrated intravenous (IV) and intraarticular (IA) use of TXA significantly reduced total blood loss, postoperative blood loss, hemoglobin (Hb) loss, and blood transfusion without ...
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