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Intravenous and topical tranexamic acid have similar efficacy in TKA
February 2016
Intravenous and topical tranexamic acid have similar efficacy in TKA
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A
One step closer to sparing total blood loss and transfusion rate in total knee arthroplasty: a meta-analysis of different methods of tranexamic acid administration.
Arch Orthop Trauma Surg. 2015 Apr;135(4):573-88.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
31 randomized controlled trials were included in this meta-analysis which was conducted with the intention of comparing systemic (intravenous (IV)) and topical (intra-articular (IA)) administration of tranexamic acid (TXA). Outcomes of interest included total blood loss, rates of transfusion, and incidence of thromboembolic events. Upon analysis of the data, it was found that there was no signific...
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