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RCT
ACE Report #7691
Ace Report Cover Arthroplasty

The effect of alendronate post-TKA on bone mineral density and clinical outcome


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Effect of one-year post-operative alendronate treatment on periprosthetic bone after total knee arthroplasty: a seven-year randomised controlled trial of 26 patients

Bone Joint J. 2015 Mar;97-B(3):337-45

Contributing Authors: AV Jaroma TA Soininvaara H Kroger

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Synopsis

26 patients who underwent total knee arthroplasty (TKA) were randomized to one of two groups: alendronate and calcium supplementation for 1 year postoperatively, or calcium alone for 1 year postoperatively. The purpose of this study was to examine the effect of alendronate on periprosthetic bone mineral density (BMD) postoperatively. Follow-up was performed for 7 years. The alendronate group demon...

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