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Efficacy of combined IV/IA TXA administration in simultaneous bilateral TKA
May 2015
Efficacy of combined IV/IA TXA administration in simultaneous bilateral TKA
Study Type:Randomized Trial
OE Level Evidence:1
Journal Level of Evidence:N/A
Reducing blood loss in simultaneous bilateral total knee arthroplasty: Combined intravenous-intra-articular tranexamic acid administration. A prospective randomized controlled trial
Knee. 2015 Mar;22(2):131-5Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
81 patients scheduled for simultaneous bilateral total knee arthroplasty were randomized to one of two groups: combined intravenous(IV)-intraarticular(IA) tranexamic acid (TXA) or placebo saline administration. The purpose of this study was to determine the efficacy of a combined TXA administration protocol for reducing blood loss postoperatively. Blood drainage, hemoglobin levels, and transfusion...
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