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ACE Report #7637
Ace Report Cover Arthroplasty

AAOS 2015: No difference between intra-articular & intravenous TXA administration in TKA

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Intravenous or Intra-articular Tranexamic Acid in Total Knee Arthroplasty

Contributing Authors: YQJ Chen PL Chin MI How HN Pang D Tay SL Chia NN Lo SJ Yeo

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


150 patients undergoing total knee arthroplasty with tourniquet application were randomized to receive tranexamic acid either intravenously or intra-articularly. The purpose of this trial was to compare the safety and effectiveness of the two administration techniques. Drain output, limb swelling, total blood loss, and incidence of complications were evaluated up to 4 days postoperatively. The res...

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