ACE Report #7624
Ace Report Cover Arthroplasty

AAOS 2015: Combined IV and local TXA administration efficacious in TKA

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Effect of use of local and systemic tranexamic acid with total knee arthroplasty

Contributing Authors: WA Nassar M Abouelsoud

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


60 patients scheduled for primary total knee arthroplasty (TKA) were randomized to one of four groups: combined intravenous and local tranexamic acid administration, intravenous TXA administration alone, local TXA administration alone, or placebo. The purpose of this study was to evaluate the efficacy of combined TXA administration in comparison to either administration route alone for reducing bl...

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