Intra-articular TXA may reduce blood loss following unilateral TKA
The reduction in blood loss with intra-articular injection of tranexamic acid in unilateral total knee arthroplasty without operative drains: a randomized controlled trialEur J Orthop Surg Traumatol. 2015 Jan;25(1):135-9.
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80 patients scheduled for primary unilateral total knee arthroplasty were randomized to receive an intra-operative, intra-articular injection of either tranexamic acid (TXA) or saline solution. This was done to determine whether intra-articular TXA injections are safe and efficacious in the reduction of blood loss and need for blood transfusion following total knee arthroplasty. Volume of blood lo...
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