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Meta-analysis
ACE Report #7418
Ace Report Cover Arthroplasty

Efficacy of various tranexamic acid administration techniques to reduce blood loss in TKA


Study Type:Meta analysis
OE Level Evidence:2
Journal Level of Evidence:2

Reduced blood loss after intra-articular tranexamic acid injection during total knee arthroplasty: a meta-analysis of the literature

Knee Surg Sports Traumatol Arthrosc. 2014 Dec;22(12):3181-90.

Contributing Authors: C Zhao-Yu G Yan C Wei L Yuejv Z Ying-Ze

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Synopsis

6 randomized controlled trials were included in this meta-analysis examining the efficacy of tranexamic acid (TXA) through intra-articular administration when compared to placebo, no TXA administration, or intravenous TXA administration. Efficacy was evaluated through blood loss, transfusion rate, and hemoglobin and hematocrit drop, and safety was assessed through the incidence of venous thromboem...

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