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Topical and intravenous tranexamic acid equally effective in total knee arthroplasty

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Ace Report Cover
February 2015

Topical and intravenous tranexamic acid equally effective in total knee arthroplasty

Vol: 4| Issue: 2| Number:59| ISSN#: 2564-2537
Study Type:Meta analysis
OE Level Evidence:2
Journal Level of Evidence:2

Comparison of topical versus intravenous tranexamic acid in primary total knee arthroplasty: A meta-analysis of randomized controlled and prospective cohort trials

Knee. 2014 Dec;21(6):987-993

Contributing Authors:
H. Wang B Shen Y Zeng

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Synopsis

Five randomized controlled trials and one prospective cohort study were analyzed with a total of 679 patients and 739 knees in this level II meta-analysis comparing topical and intravenous administration of tranexamic acid for patients undergoing total knee arthroplasty. The purpose of this analysis was to investigate whether there was a difference in efficacy between the two modes of administrati...

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