
Topical and intravenous tranexamic acid equally effective in total knee arthroplasty

Topical and intravenous tranexamic acid equally effective in total knee arthroplasty
Comparison of topical versus intravenous tranexamic acid in primary total knee arthroplasty: A meta-analysis of randomized controlled and prospective cohort trials
Knee. 2014 Dec;21(6):987-993Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Five randomized controlled trials and one prospective cohort study were analyzed with a total of 679 patients and 739 knees in this level II meta-analysis comparing topical and intravenous administration of tranexamic acid for patients undergoing total knee arthroplasty. The purpose of this analysis was to investigate whether there was a difference in efficacy between the two modes of administrati...
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