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Topical and intravenous tranexamic acid equally effective in total knee arthroplasty
February 2015
Topical and intravenous tranexamic acid equally effective in total knee arthroplasty
Study Type:Meta analysis
OE Level Evidence:2
Journal Level of Evidence:2
Comparison of topical versus intravenous tranexamic acid in primary total knee arthroplasty: A meta-analysis of randomized controlled and prospective cohort trials
Knee. 2014 Dec;21(6):987-993Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Five randomized controlled trials and one prospective cohort study were analyzed with a total of 679 patients and 739 knees in this level II meta-analysis comparing topical and intravenous administration of tranexamic acid for patients undergoing total knee arthroplasty. The purpose of this analysis was to investigate whether there was a difference in efficacy between the two modes of administrati...
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