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No significant difference between Dabigatran etexilate and enoxaparin in VTE occurrence
August 2013
No significant difference between Dabigatran etexilate and enoxaparin in VTE occurrence
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial
Lancet. 2007 Sep 15;370(9591):949-56Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
3494 patients undergoing total hip replacement were randomized to either receive 220mg of Dabigatran etexilate, 150mg of Dabigatran etexilate, or enoxaparin. The results following the treatment period (33 days) indicate that there were no significant differences between all three groups in terms of reducing the risk of major venous thromboembolism and all-cause mortality. In addition the safety ou...
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