OTA 2014: High-dose vitamin D vs. placebo in deficient patients with long bone fracture
The Effect of Acute High-Dose Vitamin D Supplementation on Fracture Union in Patients With Hypovitaminosis D: A Pilot Study
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89 of 102 enrolled patients with long bone fracture were identified as vitamin D deficient and randomized to receive a single dose of oral 100,000 IU vitamin D within the initial 2 weeks post-injury or a placebo. The purpose of this trial was to investigate the rate of nonunion in this patient population and assess the feasibility of using acute high-dose vitamin D supplementation in patients with...
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