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OTA 2014: Infection rate not significantly reduced with postoperative cefazolin after ORIF
November 2014
OTA 2014: Infection rate not significantly reduced with postoperative cefazolin after ORIF
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Do Postoperative Prophylactic Antibiotics Decrease the Risk of Postoperative Infection After ORIF?- A Prospective Double-Blinded Randomized Placebo-Controlled Trial
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CONFERENCE ACE REPORTS
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
229 patients undergoing open reduction and internal fixation (ORIF) of a closed limb fracture, with standard preoperative and intraoperative prophylactic antibiotic administration, were randomized to receive 23 hours of postoperative prophylactic cefazolin or placebo. The primary purpose of this trial was to compare infection rates between these two postoperative treatments until bony union. Resul...
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