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The effect of opioid therapy on osteoarthritis progression
November 2014
The effect of opioid therapy on osteoarthritis progression
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Progressive change in joint degeneration in patients with knee or hip osteoarthritis treated with fentanyl in a randomized trial
Yonsei Med J. 2014 Sep;55(5):1379-85Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
200 patients with hip or knee osteoarthritis (OA) were randomized to conservative treatment with loxoprofen, tramadol/acetaminophen, or transdermal fentanyl. The purpose of this study was to compare rate of OA progression in the three treatments. Patients were treated for 12 weeks with the allocated therapy, then radiographically followed-up. The results indicated that all patients experienced a s...
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