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RCT
ACE Report #709
Ace Report Cover Arthroplasty

TKA: Topical Fibrin Spray and Tranexamic acid reduce blood loss


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Comparison of topical fibrin spray and tranexamic acid on blood loss after total knee replacement: A PROSPECTIVE, RANDOMISED CONTROLLED TRIAL

J Bone Joint Surg Br. 2007 Mar;89(3):306-9

Contributing Authors: DO Molloy HA Archbold L Ogonda J McConway RK Wilson DE Beverland

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Synopsis

150 patients undergoing total knee replacement surgery were randomized to either receive topical fibrin spray, tranexamic acid, or to a control group which received no pharmacological treatment. This study aimed to compare the efficacy of these blood management treatments. The results indicated that both the topical fibrin spray and tranexamic acid were effective in reducing blood loss following t...

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