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Tranexamic acid effectively reduces blood loss after TKA without adverse events

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Ace Report Cover
October 2014

Tranexamic acid effectively reduces blood loss after TKA without adverse events

Vol: 3| Issue: 10| Number:48| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Practical issues for the use of tranexamic acid in total knee arthroplasty: a systematic review

Knee Surg Sports Traumatol Arthrosc. 2014 Aug;22(8):1849-58

Contributing Authors:
TK Kim CB Chang IJ Koh

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Synopsis

The purpose of this review was to determine the comparative efficacy between systemic and topical routes of tranexamic acid administration, optimal doses and timings, and the safety considerations of its use. 28 randomized controlled trials comparing the efficacy and safety of tranexamic acid use after total knee arthroplasty were included in this systematic review. Findings revealed both systemi...

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