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Modified release prednisone a better option at reducing morning stiffness in RA
March 2013
Modified release prednisone a better option at reducing morning stiffness in RA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints in rheumatoid arthritis (CAPRA-1): A double-blind, randomised controlled trial
Lancet. 2008 Jan 19;371(9608):205-14.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
288 patients, between the age of 18 to 80, with active rheumatoid arthritis (RA) were randomly assigned to be administered either a modified-release prednisone tablet or an immediate-release prednisone tablet. Modified-release prednisone was a safe and well tolerated drug that produced a clinically relevant reduction of morning stiffness of the joints. In addition, it provided well known therapeut...
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