To unlock this feature and to subscribe to our weekly evidence emails, please create a FREE orthoEvidence account.

SIGNUP

Already Have an Account?

Loading...
Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
Ace Report Cover

Modified release prednisone a better option at reducing morning stiffness in RA

Download
Share
Reprints
Cite This
About
+ Favorites
Share
Reprints
Cite This
About
+ Favorites
Ace Report Cover
March 2013

Modified release prednisone a better option at reducing morning stiffness in RA

Vol: 2| Issue: 2| Number:133| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints in rheumatoid arthritis (CAPRA-1): A double-blind, randomised controlled trial

Lancet. 2008 Jan 19;371(9608):205-14.

Contributing Authors:
Frank Buttgereit Gisela Doering Achim Schaeffler Stephan Witte Stanislaw Sierakowski Erika Gromnica-Ihle Slawomir Jeka Klaus Krueger Jacek Szechinski Rieke Alten

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

Synopsis

288 patients, between the age of 18 to 80, with active rheumatoid arthritis (RA) were randomly assigned to be administered either a modified-release prednisone tablet or an immediate-release prednisone tablet. Modified-release prednisone was a safe and well tolerated drug that produced a clinically relevant reduction of morning stiffness of the joints. In addition, it provided well known therapeut...

CME Image

Did you know that you’re eligible to earn 0.5 CME credits for reading this report!

LEARN MORE

Join the Conversation

Please Login or Join to leave comments.

Learn about our AI Driven
High Impact Search Feature

High Impact Icon

Our AI driven High Impact metric calculates the impact an article will have by considering both the publishing journal and the content of the article itself. Built using the latest advances in natural language processing, OE High Impact predicts an article’s future number of citations better than impact factor alone.

Continue