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Delayed LMWH lowers bleeding while maintaining DVT prophylaxis in TKA
July 2014
Delayed LMWH lowers bleeding while maintaining DVT prophylaxis in TKA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Administration of enoxaparin 24 h after total knee arthroplasty: safer for bleeding and equally effective for deep venous thrombosis prevention
Arch Orthop Trauma Surg. 2014 May;134(5):679-83. doi: 10.1007/s00402-014-1939-2. Epub 2014 Feb 18Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
210 patients undergoing primary total knee arthroplasty were randomized to administration of low-molecular-weight heparin (enoxaparin) started at either 12 hours or 24 hours after wound closure. The purpose of this study was to determine the effect of delayed LMWH administration (24h) on bleeding and the incidence of deep vein thrombosis after TKA compared to standard administration (12h). Over th...
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