Local antibiotics added to routine regimen limits infection after IM for tibia fracture
Systematic review and meta-analysis of the additional benefit of local prophylactic antibiotic therapy for infection rates in open tibia fractures treated with intramedullary nailingInt Orthop. 2014 May;38(5):1025-30
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Evidence from 21 studies (14 Retrospective or Case Studies; 6 RCTs; 1 Review) was identified using two distinct searches to evaluate the addition of locally-delivered antibiotics to prophylactic administration of systemic antibiotics in order to further limit incidence of infection of tibial fractures fixed intramedullary nailing. The evidence presented in this systematic review and meta-analysis ...
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