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Volume:3 Issue:7 Number:27 ISSN#:2563-5476
Author Verified
RCT
ACE Report #6370
Ace Report Cover Pediatric Orthopaedics

Lorazepam vs. Diazepam in the treatment of Pediatric Status Epilepticus


How to Cite

OrthoEvidence. Lorazepam vs. Diazepam in the treatment of Pediatric Status Epilepticus. ACE Report. 2014;3(7):27. Available from: https://myorthoevidene.com/AceReport/Report/6370

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Lorazepam vs Diazepam for Pediatric Status Epilepticus A Randomized Clinical Trial

JAMA. 2014 Apr 23-30;311(16):1652-60

Contributing Authors: JM Chamberlain P Okada M Holsti P Mahajan KM Brown C Vance V Gonzalez R Lichenstein R Stanley DC Brousseau J Grubenhoff R Zemek DW Johnson TE Clemons J Baren (PECARN) Pediatric Emergency Care Applied Research Network

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Synopsis

Three hundred and ten patients, aged 3 months to 18 years, exhibiting tonic-clonic status epilepticus were randomized to determine a superior treatment between lorazepam and diazepam. Goals of treatment were cessation of status epilepticus by 10 minutes, without recurrence within 30 minutes. Patients were evaluated over 4 hours after treatment, and up to 24 hours, or until hospital discharge for ...

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