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Darexaban vs placebo for prevention of VTE in Asian patients receiving TKA or THA
May 2014
Darexaban vs placebo for prevention of VTE in Asian patients receiving TKA or THA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Darexaban for the Prevention of Venous Thromboembolism in Asian Patients Undergoing Orthopedic Surgery: Results From 2 Randomized, Placebo-Controlled, Double-Blind Studies
Clin Appl Thromb Hemost. 2014 Mar;20(2):199-211Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
996 Asian patients undergoing TKA (1 study) and THA (second study) surgery were randomly assigned into 1 of 4 groups to determine if darexaban effectively and safely reduced the occurrence of venous thromboembolism (VTE) when compared to an oral placebo or subcutaneous enoxaparin. The four possible treatment methods were: a 15 or 30 mg oral dose of darexaban, a 20 mg subcutaneous injection of enox...
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