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RCT
ACE Report #6213
Ace Report Cover General Orthopaedics

WCO-IOF: Rituximab for rheumatoid arthritis positively impacts BMD of femoral neck


Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

The effect of rituximab therapy on bone mineral density with rheumatoid arthritis patients

Contributing Authors: MV Koroleva TA Raskina

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

92 patients diagnosed with rheumatoid arthritis (RA) were randomized to receive methotrexate with or without rituximab therapy to assess the impact of rituximab treatment on bone mineral density (BMD) at the femoral neck. BMD and T-scores significantly increased after 3 years in patients who received methotrexate and rituximab therapy, and maintained positive trends at the 4-year follow-up. No sig...

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