
AAOS: Fondaparinux appears to be associated with elevated blood coagulation factors

AAOS: Fondaparinux appears to be associated with elevated blood coagulation factors
Thrombogenicity and Platelet Function in Lower Extremity Total Joint Arthroplasty: A Prospective Randomized Study
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Synopsis
51 patients undergoing elective total knee and hip arthroplasty were randomized to receive thromboprophylaxis with either subcutaneous injection of fondaparinux (2.5 mg) or aspirin (325 mg) plus compression stockings. The purpose of this study was to determine whether changes in thrombogenicity can be measured with blood coagulation factors and platelet counts. Analysis of blood drawn on postopera...
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