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AAOS: Weighted and uniform doses of tranexamic acid similar in reducing blood loss in TKA
March 2014
AAOS: Weighted and uniform doses of tranexamic acid similar in reducing blood loss in TKA
Study Type:Therapy
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Weighted versus Uniform Dose of Tranexamic Acid in Total Knee Arthroplasty: A Randomized Controlled Trial
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CONFERENCE ACE REPORTS
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
50 patients undergoing primary total knee arthroplasty were randomized to receive either a uniform 1-gram dose or a weighted 20 mg/kg dose of intravenous tranexamic acid. The purpose of this study was to determine whether a uniform dose would be more effective than a weighted dose, with respect to postoperative blood loss and hemoglobin levels. Results indicated that intraoperative, postoperative,...
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