
Efficacy of ketamine, pregabalin, and combined analgesia in total hip arthroplasty

Efficacy of ketamine, pregabalin, and combined analgesia in total hip arthroplasty
The analgesic efficiency of combined pregabalin and ketamine for total hip arthroplasty: a randomised, double-blind, controlled study
Anaesthesia. 2014 Jan;69(1):46-52Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
142 patients scheduled for total hip arthroplasty were randomized to receive treatment with ketamine infusion during anaesthesia, preoperative oral pregabalin, combined ketamine and pregabalin, or placebo of both. The purpose was to determine if the combination of drugs was more efficacious than either alone. All patients received patient-controlled morphine analgesia postoperatively, and were eva...
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