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Intra-articular tranexamic acid reduces blood loss & transfusion requirements after TKA
February 2014
Intra-articular tranexamic acid reduces blood loss & transfusion requirements after TKA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Topical (Intra-Articular) Tranexamic Acid Reduces Blood Loss and Transfusion Rates Following Total Knee Replacement: A Randomized Controlled Trial (TRANX-K)
J Bone Joint Surg Am. 2013 Nov 6;95(21):1961-8Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred and fifty seven patients who underwent total knee arthroplasty were enrolled in this study to determine the effects of topically applied intra-articular tranexamic acid on blood loss and transfusion requirements. Patient’s wounds were randomized to be sprayed with 1 g of tranexamic acid in 50 mL of saline solution or simply 50 mL of saline solution. The results suggest that topical tra...
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