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RCT
ACE Report #5461
Ace Report Cover General Orthopaedics

Alendronate is an effective way of increasing BMD and reducing bone turnover


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

The safety and efficacy of early-stage bi-weekly alendronate to improve bone mineral density and bone turnover in chinese post-menopausal women at risk of osteoporosis

J Int Med Res. 2011;39(1):302-10

Contributing Authors: L You ZY Sheng JY Chen L Pan L Chen

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Synopsis

180 post-menopausal Chinese women, between 40 and 70 years of age, with osteopenia (T-score between -1.6 and -2.4), were randomized into 1 of 2 groups to study the effects of early antiresorptive drug intervention on osteopenia. The first group, classified as the treatment group, was given received 70 mg of alendronate once every 2 weeks plus 0.5 micrograms of alfacalcidol daily, while the second ...

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