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Volume:3 Issue:9 Number:33 ISSN#:2563-5476
RCT
ACE Report #5228
Ace Report Cover Arthroplasty

Enoxaparin superior to warfarin in prevention of venous thromboembolism after primary TKA


How to Cite

OrthoEvidence. Enoxaparin superior to warfarin in prevention of venous thromboembolism after primary TKA. ACE Report. 2014;3(9):33. Available from: https://myorthoevidene.com/AceReport/Report/5228

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Prevention of venous thromboembolic disease following primary total knee arthroplasty. A randomized, multicenter, open-label, parallel-group comparison of enoxaparin and warfarin

J Bone Joint Surg Am. 2001 Jun;83-A(6):900-6

Contributing Authors: Fitzgerald RH TE Spiro AA Trowbridge Gardiner GA TL Whitsett MB O'Connell JA Ohar TR Young Enoxaparin Clinical Trial Group

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Synopsis

349 patients undergoing knee arthroplasty were randomized to receive thromboprophylaxis with enoxaparin or warfarin postoperatively. Patients were assessed for venous thromboembolism defined as deep vein thrombosis and pulmonary vein thrombosis. Enoxaparin was significantly more effective than adjusted‐dose warfarin in reducing the occurrence of asymptomatic venous thromboembolism, including proxi...

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