Similar infection rates with the use of erythromycin and colistin-loaded cement in TKA
The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 kneesJ Bone Joint Surg Am. 2013 May 1;95(9):769-74. doi: 10.2106/JBJS.L.00901
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3000 patients undergoing total knee arthroplasty (TKA) (2948 of whom completed the study) were randomized to the use of either antibiotic-loaded or non-antibiotic-loaded cement in the fixation of their prosthesis. The primary goal of this study was to compare infection rates between the two groups and the secondary goal was to determine if risk factors existed for deep infection. Results indicated...
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