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Strontium ranelate improves radiological and clinical outcome in patients with knee OA
April 2013
Strontium ranelate improves radiological and clinical outcome in patients with knee OA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial
Ann Rheum Dis. 2013 Feb;72(2):179-86. doi: 10.1136/annrheumdis-2012-202231. Epub 2012 Nov 1Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
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Dr. Reginster discusses strontium ranelate effect the on radiological and clinical progression of knee osteoarthritis
Synopsis
1683 patients were randomized to assess the effect of strontium ranelate on radiological and clinical progression of knee osteoarthritis (OA). Patients received either strontium ranelate 1 g/day, 2 g/day, or placebo and were assessed over 3 years. Results revealed that treatment with strontium ranelate (1 and 2 g/day) was associated with a significant effect on structure in knee OA patients. Treat...
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