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Volume:1 Issue:11 Number:7 ISSN#:2563-5476
Author Verified
ACE Report #4546
Ace Report Cover Pediatric Orthopaedics

Long bone fractures: Addition of midazolam to morphine does not improve pain relief

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Comparison of a morphine and midazolam combination with morphine alone for paediatric displaced fractures: a randomized study

Acta Paediatr. 2011 Nov;100(11):e203-7. doi: 10.1111/j.1651-2227.2011.02311.x. Epub 2011 May 11

Contributing Authors: C Wille-Ledon H Chappuy C Giraud JM Treluyer G Cheron

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58 children with long-bone fractures were randomized to either receive oral morphine combined with sublingual midazolam or morphine combined with sublingual placebo, to determine which combination of drugs best alleviated pain. At 120 minutes after drug administration, there were no significant differences between patients who received morphine alone or morphine combined with midazolam.

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