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Addition of magnesium sulfate to bupivacaine prolongs onset and duration of sensory block
July 2013
Addition of magnesium sulfate to bupivacaine prolongs onset and duration of sensory block
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Effects of adjunct intrathecal magnesium sulfate to bupivacaine for spinal anesthesia: a randomized, double-blind trial in patients undergoing lower extremity surgery
J Anesth. 2011 Dec;25(6):892-7. doi: 10.1007/s00540-011-1227-z. Epub 2011 Sep 18Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
79 patients undergoing lower extremity orthopedic surgery were randomized to examine the effect of additional magnesium sulfate (MgSO4) to bupivacaine on spinal anesthesia. Patients received either 100 mg magnesium sulfate 5% (0.2 ml) with 15 mg bupivacaine 0.5% or 15 mg bupivacaine 0.5% plus 0.2 ml normal saline (control). Assessment after the first 24 hours revealed that the addition of magnesiu...
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