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Volume:1 Issue:5 Number:123 ISSN#:2563-5476
RCT
ACE Report #440
Ace Report Cover Spine

Vertebroplasty no more effective than placebo in treating osteoporotic spinal fractures


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

A Randomized Trial of Vertebroplasty for Osteoporotic Spinal Fractures

N Engl J Med. 2009 Aug 6;361(6):569-79.

Contributing Authors: DF Kallmes BA Comstock PJ Heagerty JA Turner DJ Wilson TH Diamond R Edwards LA Gray L Stout S Owen W Hollingworth B Ghdoke DJ Annesley-Williams SH Ralston JG Jarvik

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Synopsis

131 patients suffering from chronic pain due to vertebral compression fractures (1-3) were randomized to receive either a vertebroplasty or a sham procedure. The goal of this study was to evaluate the efficacy of vertebroplasty in the treatment of painful vertebral fractures. At the one month follow-up, both the vertebroplasty and placebo groups demonstrated improvements in pain measures from base...

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