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Volume:1 Issue:8 Number:580 ISSN#:2563-5476
RCT
ACE Report #4385
Ace Report Cover Metabolic Disorders

Aspirin reduces risk of recurrence in patients with unprovoked venous thromboembolism


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Aspirin for preventing the recurrence of venous thromboembolism

N Engl J Med. 2012 May 24;366(21):1959-67. doi: 10.1056/NEJMoa1114238

Contributing Authors: C Becattini G Agnelli A Schenone S Eichinger E Bucherini M Silingardi M Bianchi M Moia W Ageno MR Vandelli E Grandone P Prandoni WARFASA Investigators

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Synopsis

Two weeks following the completion of treatment with vitamin K antagonists, 403 patients with a previous unprovoked venous thromboembolism (VTE) were randomised into two groups. Patients either received 100 mg aspirin or a placebo, once per day for 2 years, to measure the recurrence of VTE. Following assessments every 3 months in the first year and every 6 months in the second year, the results de...

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