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Denosumab reduces risk of fractures in post-menopausal women
May 2013
Denosumab reduces risk of fractures in post-menopausal women
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis
N Engl J Med. 2009 Aug 20;361(8):756-65. Epub 2009 Aug 11.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
7868 women with osteoporosis, having a bone mineral density T score of less than -2.5 but no less than -4.0, were randomized to receive either injection with denosumab or an injection with placebo. Denosumab has been proposed to decrease bone resorption and thus improve bone mineral density in those patients with osteoporosis. This study aimed to assess the efficacy of denosumab injection as a tre...
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