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TKA: Intra-articular tranexamic acid reduces blood loss and transfusion requirements

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Ace Report Cover
May 2013

TKA: Intra-articular tranexamic acid reduces blood loss and transfusion requirements

Vol: 2| Issue: 4| Number:156| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Efficacy of intra-articular tranexamic acid in blood loss reduction following primary unilateral total knee arthroplasty

Knee Surg Sports Traumatol Arthrosc. 2012 Dec;20(12):2494-501. doi: 10.1007/s00167-012-1942-5. Epub 2012 Mar 15

Contributing Authors:
SP Roy UF Tanki A Dutta SK Jain ON Nagi

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Synopsis

Fifty patients with knee osteoarthritis undergoing primary unilateral cemented-TKA were randomized to receive either intra-articular tranexamic acid (TA) or saline solution (control). After the first 48 hours, the parameters related to the drain output were compared between the two groups. Blood loss on 5th post-operative day was also noted. Results demonstrated that patients who received tranexam...

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