To unlock this feature and to subscribe to our weekly evidence emails, please create a FREE orthoEvidence account.

SIGNUP

Already Have an Account?

Loading...
Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
Vol:2 Issue:3 Number:12 ISSN#:2564-2537
DOWNLOAD ESPAÑOL
Author Verified
RCT
ACE Report #4343
Ace Report Cover Tumour

Osteosarcoma: 25 year survival rate significantly improved with adjuvant chemotherapy


How to Cite

OrthoEvidence. Osteosarcoma: 25 year survival rate significantly improved with adjuvant chemotherapy. ACE Report. 2013;2(3):12. Available from: https://myorthoevidence.com/AceReport/Report/4343

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Long-term results (>25 years) of a randomized, prospective clinical trial evaluating chemotherapy in patients with high-grade, operable osteosarcoma

Cancer. 2012 Dec 1;118(23):5888-93

Contributing Authors:
NM Bernthal N Federman FR Eilber SD Nelson JJ Eckardt FC Eilber WD Tap

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

Synopsis

59 patients who underwent treatment for stage IIA/IIB, intramedullary, high-grade osteosarcoma, between 1981 and 1984, were randomized to receive either T-10B protocol adjuvant chemotherapy or no adjuvant chemotherapy following definitive surgical resection. Improvements in disease-free survival (DFS) and overall survival (OS) were monitored over 25 years, and tumor necrosis was evaluated for impl...

Ace Report Preview Image
CME Image

Continuing Medical Education Credits

You could be earning 0.5 CME credits for each report you read.

LEARN MORE
For Reprints and Permissions, click here

Please Login or Join to leave comments.